Table 2.

Characteristics, shift profiles, shift reasons of participants who experienced changes in gender-related medical request

Profile							Ongoing Gender Discovery			Interpersonal Influences
	Participant	Autistic?	Gender at baseline	Sex assigned at birth	Ages followed	Treatment requested	Wants more life experiences	Exploring gender identity	Shifts in gender identity	Worries about coming out	Lack of support for gender	Perceived peer pressure	Delusions/thought instability	Reluctance towards maleness
Profile 1 (25%) Requests ➔ No Longer Requests	1	N	M	F	17	H		*	✓		✓			✓
	2	N	M	F	14–15	H/S			✓
	3	Y	F	M	16	H			✓
	4	Y	F	M	18–22	H/S		✓
	5	Y	F	M	14	H			✓	✓
Profile 2 (45%) Requests ➔ No Longer Requests ➔ Requests	6	N	F	M	16–17	H	✓	*		✓
	7	N	F	M	16–18	H		✓
	8	N	M	F	15–18	H		✓				✓
	9	Y	NB	F	16–18	S	✓
	10	Y	NB	F	12–17	H/S			✓			✓
	11	N	F	M	4–19	H		✓	✓
	12	Y	NB	F	12–16	H		*	✓
	13	Y	NB	F	16–20	H	✓	*
	14	Y	F	M	12–15	H		*
Profile 3 (5%) Requests ➔ No Longer Requests ➔ Considering	15	N	M/NB	F	17–20	S		*
Profile 4 (10%) Requests ➔ Oscillation ➔ Requests/No Longer Requests	16a	Y	Q	M	17	H/S							✓
	17b	N	M	F	15–20	S			✓				✓
Profile 5 (10%) Requests ➔ Treatment Completed	18	N	M	F	16–18	H			✓
	19	Y	NB	F	17–20	H								✓
Profile 6 (5%) Requests ➔ Treatment Terminated	20	N	F	M	12–17	H							✓
Inter-rater reliability (κ)							0.77	0.34	0.50	1.00	0.64	0.77	0.77	0.77

Legend:

^aended at no longer requests

^bended at requests

^*= inconsistencies between coders Y = has autism diagnosis

N = does not have autism diagnosis

M = transmasculine gender identity or male sex designated at birth F = transfeminine gender identity or female sex designated at birth Q = queer

NB = nonbinary gender

H = gender-affirming hormone therapy (excludes blockers) S = gender-affirming surgery