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. 2023 Feb 28;9:30. doi: 10.1038/s41531-023-00468-2

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a–c Plots show baseline concentrations of each specific BMP isoform in the six groups indicated on the X -axis. Box-and-whisker plots with scatter plots superimposed are shown with each filled circle representing observed data. The bottom and top edges of the box correspond to the 75th and 25th percentiles, respectively. The horizontal line within the box indicates the median. The whiskers indicate the range of values within 1.5 times the interquartile range. A Rank-based linear model with adjustment for age and sex was used for pairwise comparisons. The significance level for pairwise comparisons is p value <0.0125 (after Bonferroni correction). ****p value <0.0001.