Fig. 1.

⁴⁴Ti/⁴⁴Sc generator and ⁴⁴Sc elution. A Pilot micro-scale generator with uni-directional elution; B Clinical-scale modular generator with bidirectional elution; C Elution profiles of ⁴⁴Sc with a mobile phase of 0.05 M HCl at a flow rate of 1.0 mL/min, which was monitored in situ with in-line gamma detector; D A consistent amount of ⁴⁴Sc activity is collected after loading to the modular generator; E ⁴⁴Sc/⁴⁴Ti ratio in the eluted ⁴⁴Sc solution. E4 to E11 elution is bidirectional without additional ZR resin cartridge; E12 to E19 elution is bidirectional with an additional ZR resin cartridge