Table 3.
Changes in vascular risk factor after the diet intervention (T1, 3 months).
| After phytate diet (T1) | After non-phytate diet (T1) | ||||
|---|---|---|---|---|---|
| Median (Q1–Q3) | T1 vs T0 P value | Median (Q1–Q3) | T1 vs T0 P value | Intergroup P value | |
| Weight (kg) | 87 (80–93) | 0.572 | 87 (79–93) | 0.457 | 0.828 |
| BMI (kg/m2) | 36 (33–39) | 0.638 | 36 (33–39) | 0.650 | 0.666 |
| Waist (cm) | 108 (102–116) | 0.358 | 108 (102–115) | 0.781 | 0.371 |
| Hip (cm) | 110 (103–116) | 0.140 | 108 (103–118) | 0.307 | 0.195 |
| Waist/hip | 1.00 (0.93–1.02) | 0.876 | 0.99 (0.97–1.01) | 0.480 | 0.478 |
| Glucose (mg/dL) | 171 (137–207) | 0.448 | 154 (123–203) | 0.760 | 0.548 |
| Total cholesterol (mg/dL) | 166 (147–190) | 0.950 | 161 (134–180) | 0.073 | 0.155 |
| LDL cholesterol (mg/dL) | 89 (76–117) | 0.725 | 90 (67–115) | 0.451 | 0.380 |
| HDL cholesterol (mg/dL) | 40 (34–47) | 0.080 | 42 (36–48) | 0.210 | 0.060 |
| Triglycerides (mg/dL) | 161 (88–226) | 0.210 | 122 (97–159) | 0.182 | 0.045 |
| Insulin (µUI/mL) | 17 (12–35) | 0.396 | 20 (13–33) | 0.811 | 0.330 |
| Lipoprotein A (mg/dL) | 19.2 (3.9–83.8) | 0.225 | 17.3 (4.1–54.6) | 0.245 | 0.225 |
| hs-CRP (mg/dL) | 0.30 (0.21–0.73) | 0.446 | 0.36 (0.18–0.70) | 0.105 | 0.830 |
| Iron (µg/dL) | 74 (56–97) | 0.035 | 70 (57–91) | 0.170 | 0.194 |
| Ferritin (ng/mL) | 46 (25–106) | 0.736 | 45 (18–80) | 0.347 | 0.935 |
| Transferrin (mg/dL) | 262 (239–282) | 0.214 | 265 (251–287) | 0.377 | 0.189 |
| Transferrin saturation index (%) | 21 (16–26) | 0.061 | 20 (16–25) | 0.309 | 0.169 |
| Vitamin B12 (pg/mL) | 391 (266–473) | 0.219 | 336 (242–429) | 0.399 | 0.915 |
| Folate (ng/mL) | 6.9 (5.1–12.6) | 0.723 | 6.8 (5.3–8.8) | 0.899 | 0.954 |
| Leukocytes (×109/L) | 8.5 (6.5–9.5) | 0.416 | 7.8 (6.4–9.6) | 0.681 | 0.372 |
| Lymphocytes T1 (×109/L) | 2.5 (1.9–3.2) | 0.470 | 2.4 (1.9–2.8) | 0.450 | 0.295 |
| Lymphocytes (%) | 32 (27–36) | 0.399 | 31 (27–37) | 0.865 | 0.456 |
| Platelets (×106/L) | 263 (226–322) | 0.688 | 257 (217–319) | 0.407 | 0.358 |
| HOMA IR | 0.80 (0.54–1.04) | 0.473 | 0.72 (0.52–1.45) | 0.473 | 0.266 |
Un-adjusted within groups changes (before, T0 vs. after intervention, T1) are given as median (interquartile range). Intra-groups analysis (T0 vs. T1) used a paired-sample Wilcoxon signed-rank test or paired-samples t test to determine the significance of differences. Intergroup analysis (InsP6 diet vs, non-InsP6 diet) used analysis of covariances and comparison between groups after adjusting for baseline levels to determine the significance of differences. After Bonferroni correction, the statistical threshold was adjusted to P<0.05/24 = 0.002.