Table 2.
Odds ratio for the association of extreme Lp(a) with cardiovascular outcomes.
| Variable | Odds ratio (univariate) | P value | Odds ratio (multivariatea) | P value |
|---|---|---|---|---|
| Myocardial infarction | 3.84 (1.60–9.20) | 0.003 | 2.50 (1.20–5.21) | 0.014 |
| Coronary artery disease | 4.18 (1.85–9.54) | 0.001 | 2.20 (1.20–4.05) | 0.011 |
| PAD or stroke | 2.29 (0.79–6.66) | 0.127 | 2.75 (0.88–8.64) | 0.083 |
| Overall ASCVD | 2.72 (1.24–5.97) | 0.012 | 1.65 (0.95–2.88) | 0.077 |
ASCVD, atherosclerotic cardiovascular disease; PAD, peripheral artery disease.
a
Adjusted for hypertension, smoking, diabetes mellitus, chronic kidney disease, family history of cardiovascular disease, obesity (body mass index ≥30 kg/m2), prior malignancy, and baseline LDL-C levels (in addition to age- and sex-matching by design).