Post-treatment tumor stromal PD-L1 level and pretreatment serum PD-L1 level both predict preoperative chemotherapy response
(A) Treatment response in patients (N = 70) with different stromal/tumor PD-L1 staining scores. p value was calculated by chi-squared test.
(B) Stromal PD-L1 staining scores of patients with different treatment responses. p value was calculated by chi-squared test.
(C) Responders (N = 18) had lower serum PD-L1 level before treatment compared with non-responders (N = 19).
(D) ROC curve demonstrating the treatment response predictive accuracy of pretreatment serum PD-L1 level.
(E) Post-treatment serum PD-L1 level showed no difference between responders (N = 18) and non-responders (N = 19).
(F) ROC curve demonstrated the treatment response predictive accuracy of post-treatment serum PD-L1 level.
See also Figure S4.