FIGURE 1.
Selective sites of neuronal death in some neurodegenerative diseases. Pyramidal neurons in the entorhinal cortex layer II and hippocampus layer CA1 in Alzheimer’s disease (AD), dopaminergic neurons in the substantia nigra pars compacta in Parkinson’s disease (PD), GABAergic spiny projection and cholinergic neurons in the striatum, and pyramidal neurons in the cortex in Huntington’s disease (HD), and motor neurons in the motor cortex, brainstem or spinal cord in amyotrophic lateral sclerosis (ALS).