Table 2.

Summary of bone lesions treated with radiation therapy

	Yang Zu. et al.65	Li et al.66	Feng et al.67	Yao et al.68	Jiao et al.70	Zhang et al.71	Xie et al.73	Yang Zu et al.74	Wang C et al.75	Wang W et al.76	Lu et al.77	Chen et al.78	Yang Ze et al.79	Xiang et al.81
#	50	29	26	24	38	33	161	40	22	133	49	11	14	96
PELVIC	+	-	-	-	+	n.d	-	-	+	+	-	-	-	+
RIB	+	-	-	-	+	n.d	-	-	-	+	-	-	+	+
VERTEBRA, C -T	+	+	+	+	+	n.d	+	+	-	+	+	+	-	+
VERTEBRA, L-S	+	+	+	+	+	n.d	+	+	-	+	+	+	-	+
SCAPULA	+	-		-	+	n.d	-	-	-	+	+	-	-	+
CLAVICULA	+	-		-	+	n.d	-	-	-	+	-	-	-	+
EXTREMITY	+	-		-	+	n.d	-	-	-	+	-	-	-	+
SACRUM	-	+		-	+	n.d	-	-	-	+	-	-	+	+
STERNUM	-	-		-	+	n.d	-	-	-	-	-	-	+	-
SKULL	-	-		-	-	n.d	-	-	-	+	-	-	-	-
OSTEOLYTIC	-	29		n.d	27	n.d	-	n.d	n.d	n.d	n.d	n.d	n.d	49
OSTEOPLASTIC	50	-	n.d	n.d	6	n.d	-	n.d	n.d	n.d	n.d	n.d	n.d	15
MIXED	-	-	n.d	n.d	5	n.d	-	n.d	n.d	n.d	n.d	n.d	n.d	12
RADIATION SOURCE	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds	I-125 seeds
RESULTS	125I + PVP significant better	Multineedle is better than single needle	effective after EBRT failure	125I reirradiation is feasible in vertebral mets	RFA better at 1 month No diff. at 3 months	RFA+125I better than RFA alone	125I+ PVP significant better	PVP+125I significant better	2 yrs OS 45,5% 2 yrs LC 36,4%	Safe and effective	PVP + 125I Is better as PVP + RFA	Pre-plan differ from final applied dose	125I + chemoem-bolisation effective and feasible	PVP + 125I better than PVP+ EBRT

EBRT, external beam radiotherapy; HDR, high-dose-rate interventional radiotherapy(brachytherapy); LC, local control; OS, overall survival; PVP, percutaneous vertebroplasty; RFA, radiofrequency ablation.

# number of implanted targets; n.d. = no data; *femur intramedullary metastasis of melanoma.