Table 3.
LASSO coefficient profiles of the 20 features in Model 6
| ROI | Radiomics Features | Modality | Coefficient |
|---|---|---|---|
| Intratumoral | wavelet-HHL_gldm_LargeDependenceEmphasis | Recombined | 0.054211969 |
| wavelet-HLL_glszm_ZonePercentage | Low-energy | −0.027478837 | |
| wavelet-HLL_glszm_ZonePercentage | Recombined | −0.002436579 | |
| wavelet-HLL_gldm_SmallDependenceLowGrayLevelEmphasis | Low-energy | −0.012799902 | |
| wavelet-LHH_glszm_LowGrayLevelZoneEmphasis | Low-energy | 0.037350932 | |
| wavelet-LHL_glrlm_ShortRunEmphasis | Recombined | −0.005482193 | |
|
Intratumoral +Peritumoral 10 mm |
wavelet-HHL_glszm_LargeAreaHighGrayLevelEmphasis | Low-energy | 0.034885685 |
| wavelet-HHH_glrlm_GrayLevelVariance | Low-energy | 0.024310428 | |
| wavelet-HHH_glrlm_ShortRunEmphasis | Recombined | −0.016050074 | |
| wavelet-HHH_glrlm_ShortRunLowGrayLevelEmphasis | Low-energy | −0.010330209 | |
| wavelet-LHL_gldm_LargeDependenceHighGrayLevelEmphasis | Recombined | 0.034539233 | |
| wavelet-LLH_glszm_SizeZoneNonUniformity | Recombined | 0.036595107 | |
| wavelet-LLL_glszm_ZonePercentage | Low-energy | −0.029445573 | |
| wavelet-HHH_glrlm_GrayLevelNonUniformityNormalized | Recombined | −0.019092896 | |
| wavelet-HLL_firstorder_Kurtosis | Low-energy | 0.034413406 | |
| wavelet-LLH_glszm_SmallAreaEmphasis | Recombined | 0.00273036 | |
| wavelet-LLL_glrlm_RunLengthNonUniformity | Low-energy | −0.000597858 | |
| wavelet-HHL_glszm_SizeZoneNonUniformityNormalized | Low-energy | −0.047975366 | |
| wavelet-LLL_firstorder_InterquartileRange | Low-energy | 0.014380025 | |
| wavelet-HLL_glszm_SmallAreaEmphasis | Low-energy | 0.003804684 |