Table 2. Diagnostic Performance of SF-FFR versus CFD-FFR for Demonstration of Ischemia (FFR ≤ 0.80).
| Method | TP | TN | FP | FN | Sensitivity | Specificity | PPV | NPV | Accuracy | |
| FN: false negative; FP: false positive; NPV: negative predictive value; PPV: positive predictive value; TN: true negative; TP: true positive. | ||||||||||
| Patient level | SF-FFR | 34 | 24 | 2 | 4 | 0.89 (0.81,0.97) | 0.92 (0.82,1.00) | 0.94 (0.88,1.00) | 0.86 (0.75,0.96) | 0.91 (0.84,0.97) |
| CFD-FFR | 32 | 23 | 3 | 6 | 0.84 (0.74,0.94) | 0.88 (0.77,0.97) | 0.91 (0.83,0.97) | 0.79 (0.66,0.92) | 0.86 (0.78,0.92) | |
| P-value | 0.731 | 0.995 | − | − | 0.552 | |||||
| Vessel level | SF-FFR | 39 | 28 | 4 | 4 | 0.91 (0.83-0.98) | 0.88 (0.78-0.97) | 0.91 (0.83-0.98) | 0.88 (0.78-0.97) | 0.89 (0.84-0.94) |
| CFD-FFR | 36 | 29 | 3 | 7 | 0.84 (0.74-0.93) | 0.91 (0.81-0.98) | 0.92 (0.85-0.98) | 0.81 (0.69-0.91) | 0.87 (0.80-0.93) | |
| P-value | 0.344 | 0.999 | − | − | 0.603 | |||||