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. 2023 Feb 15;10:1057643. doi: 10.3389/fmed.2023.1057643

Table 2.

CTD-IP cases. Patients are allocated according to fulfillment of classification criteria for the different connective tissue diseases (CTD) at the end of follow-up.

Rheumatoidarthritis Systemicsclerosis Inflammatorymyopathy Sjögren Lupus Mixedconnectivetissuedisease
Number 21 + 1 overlapping case 14 + 2 ovarlapping cases 20 + 1 overlapping case 4 + 1 overlapping case 1 ovarlapping case 1
Women, n (%) 16 (73) 12 (75) 15 (75) 4 (100) 1 (100) 1 (100)
Eversmoker, n (%) 10 (48) 4 (29) 14 (67)
Smoking status, n: never, past, active smoker 12, 5, 5 12, 4, 0 7, 7, 7 4, 0, 0 1, 0, 0 1, 0, 0
Age at onset, mean (SEM) median 60.1 (3.4) 62 46.8 (4.5) 48 51.8 (2.4) 53.5
Age at endpoints, mean (SEM) median 76.3 (2.4) 80 61.4 (3.9) 63 60.8 (2) 61.5
Disease duration, mean (SEM) median 9.1 (1.5) 8 9.1 (1.3) 8.5 6.8 (1.1) 6.5
Follow-up, (patient-years) 200 146 139 53 9 3
Respiratory onset, n 4 3 3 2 0 0
Extra-respiratory onset, n 18 10 5 2 1 1
Synchronic pulmonary and extra pulmonary disease at onset, n 0 3 13 1 0 0