Table 3.

Longitudinal associations between study factors and diastolic blood pressure.

	Unadjusted, mmHg		Adjusted, mmHg
	Effect (95 % CI)	p-value	Effect (95 % CI)	p-value
Age, per 10 years	1.10 (-0.23, 2.43)	0.10
Race/Ethnicity
White	Ref		Ref
Black/African American	6.89 (3.47, 10.31)	<0.001	4.61 (1.32, 7.89)	0.006
Latina	0.99 (-3.40, 5.38)	0.66	0.63 (-3.51, 4.78)	0.76
Multiracial	5.14 (0.35, 9.93)	0.04	3.04 (-1.51, 7.59)	0.19
Other	−0.16 (-5.36, 5.03)	0.95	−1.34 (-6.20, 3.53)	0.59
Post-menopausal	1.91 (-0.67, 4.49)	0.15
Diabetes	0.31 (-3.03, 3.65)	0.86
Prior myocardial infarction	−0.61 (-2.33, 1.11)	0.49
Prior stroke	0.22 (-0.76, 1.20)	0.66
HIV-positive	−2.69 (-5.69, 0.31)	0.08
History of Hepatitis C infection	−1.73 (-4.25, 0.80)	0.18
Body Mass Index (BMI)	0.14 (-0.01, 0.30)	0.07	0.19 (0.04, 0.34)	0.02
LDL cholesterol, per SD (mg/dL)	1.58 (0.56, 2.60)	0.003	1.41 (0.42, 2.41)	0.005
HDL cholesterol, per SD (mg/dL)	2.41 (1.34, 3.49)	<0.001	2.20 (1.12, 3.27)	<0.001
C-reactive protein	−0.20 (-0.69, 0.29)	0.43
Estradiol	0.00 (-0.01, 0.01)	0.83
Cocaine	2.28 (0.19, 4.38)	0.03	2.83 (0.72, 4.94)	0.009
Cocaethylene	−0.20 (-2.48, 2.08)	0.86
Levamisole	1.06 (-0.79, 2.91)	0.26
Methamphetamine	1.27 (-0.84, 3.38)	0.24
Heroin/Mono-acetylmorphine-6	0.16 (-4.48, 4.80)	0.95
Fentanyl/Norfentanyl	2.21 (-2.16, 6.58)	0.32
Additional opioids	−0.77 (-3.11, 1.56)	0.52
Alcohol	0.90 (-1.02, 2.83)	0.36
Cannabis (THC)	−1.40 (-3.26, 0.46)	0.14
Cotinine/Nicotine	−0.12 (-2.24, 2.00)	0.91
Benzodiazepine	−1.82 (4.47, 1.10)	0.22
Naloxone	2.65 (-19.61, 24.91)	0.82
Methadone	−4.94 (-7.66, −2.23)	<0.001	−4.47 (-7.12, −1.81)	<0.001
Buprenorphine/ Norbuprenorphine	−0.86 (-9.29, 7.56)	0.84
Beta blockers	−1.27 (-4.89, 2.35)	0.49
Calcium channel blocker	−3.20 (-7.08, 0.67)	0.11
Other Antihypertensive	−1.74 (-5.74, 2.25)	0.39
Statin	−1.24 (-8.24, 5.75)	0.73
Lidocaine	−0.86 (-2.96, 1.24)	0.42
Acetaminophen	−0.08 (-1.71, 1.55)	0.92
Any HIV medication	−0.61 (-2.86, 1.65)	0.60