Table 1.
Patient characteristics.
| Fresh samples | Paraffin samples | |||||||
|---|---|---|---|---|---|---|---|---|
| Total | HPV+ | HPV− | P | Total | HPV+ | HPV− | P | |
| Variables | n = 55 (100.0) | n = 37 (67.3) | n = 18 (32.7) | value | n = 78 (100.0) | n = 36 (46.2) | n = 42 (53.8) | value |
| Age medium (range) | 56 (22–77) | 55 (22–77) | 54 (48–77) | 0.002a | 57 (22–80) | 51 (22–74) | 58 (36–80) | 0.026a |
| Gender, N (%) | ||||||||
| Male | 46 (83.6) | 29 (52.7) | 17 (30.9) | 0.262 | 69 (88.5) | 29 (37.2) | 40 (51.3) | 0.095 |
| Female | 9 (16.4) | 8 (14.5) | 1 (1.8) | 9 (11.5) | 7 (9.0) | 2 (2.6) | ||
| Smoking, N (%) | ||||||||
| No | 21 (57.1) | 18 (32.7) | 3 (5.5) | 0.022 | 38 (48.7) | 21 (26.9) | 17 (21.8) | 0.116 |
| Yes | 34 (42.9) | 19 (34.5) | 15 (27.3) | 40 (51.3) | 15 (19.2) | 25 (32.1) | ||
| Anatomic site, N (%) | ||||||||
| Tonsil | 46 (83.6) | 34 (61.8) | 12 (21.8) | 37 (47.4) | 23 (29.5) | 14 (17.9) | ||
| Base of tongue | 4 (7.3) | 2 (3.6) | 2 (3.6) | 0.037b | 30 (38.5) | 11 (14.1) | 19 (24.4) | 0.032b |
| Soft palate | 4 (7.3) | 1 (1.8) | 3 (5.5) | 4 (5.1) | 1 (1.3) | 3 (3.8) | ||
| Other | 1 (1.8) | 0 (0) | 1 (1.8) | 7 (9.0) | 1 (1.3) | 6 (7.7) | ||
| T Stage, N (%) | ||||||||
| T1 | 5 (9.1) | 3 (5.5) | 2 (3.6) | 17 (21.8) | 9 (11.5) | 8 (10.3) | ||
| T2 | 27 (49.1) | 20 (36.4) | 7 (12.7) | 0.115b | 31 (39.7) | 16 (20.5) | 15 (19.2) | 0.110b |
| T3 | 18 (32.7) | 13 (23.6) | 5 (9.1) | 24 (30.8) | 11 (14.1) | 13 (16.7) | ||
| T4 | 5 (9.1) | 1 (1.8) | 4 (7.3) | 6 (7.7) | 0 (0) | 6 (7.7) | ||
| N Stage, N (%) | ||||||||
| N0 | 1 (1.8) | 1 (1.8) | 0 (0) | 4 (5.1) | 1 (1.3) | 3 (3.8) | ||
| N1 | 27 (49.1) | 25 (45.5) | 2 (3.6) | 0.000b | 24 (30.8) | 21 (26.9) | 3 (3.8) | 0.000b |
| N2 | 12 (21.8) | 3 (5.5) | 9 (16.4) | 17 (21.8) | 12 (15.4) | 5 (6.4) | ||
| N3 | 15 (27.3) | 8 (14.5) | 7 (12.7) | 33 (42.3) | 2 (2.6) | 31 (39.7) | ||
| Tumor Stage, N (%) | ||||||||
| I | 18 (32.7) | 18 (32.7) | 0 (0) | 23 (29.5) | 17 (21.8) | 6 (7.7) | ||
| II | 10 (18.2) | 10 (18.2) | 0 (0) | 0.000b | 20 (25.6) | 17 (21.8) | 3 (3.8) | 0.000 |
| III | 11 (20.0) | 9 (16.4) | 2 (3.6) | 10 (12.8) | 2 (2.6) | 8 (10.3) | ||
| IV | 16 (29.1) | 0 (0) | 16 (29.1) | 25 (32.1) | 0 (0) | 25 (32.1) | ||
at test.
bFisher exact test.