Comparison of the total number of analytes with fold changes exceeding given acceptance criteria for different storage conditions was undertaken. The proportion of fold changes above ± 20 % for individual conditions and ± 30 % for combined conditions is indicated by the colors of the tiles. Numbers within the tiles represent the number of analytes with out-of-range concentration changes. The first four columns represent the tested conditions (combination of storage matrix, temperature, and duration). The last two columns display a combined evaluation of fold changes, depending on the combination of pre-analytical sample conditions (whole blood and plasma stored in ice water or at RT, respectively, for different periods of time).