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. 2023 Feb 15;5:1009638. doi: 10.3389/fmedt.2023.1009638

Figure 2.

Figure 2

Clinical trial workflow. (A) ABY-029 was administered via 5 ml intravenous bolus injection 1–3 h prior to surgery. (B) Each patient underwent standard-of-care surgery, and gross surgical specimens were collected. (C) After surgery, specimens were sectioned in bread-loafed slices, formalin-fixed, and paraffin-embedded, then cut into consecutive slides for staining. Closed-field fluorescence imaging was performed on the bread-loafed slices. Histology slides from bread-loafed slices underwent standard histopathological examination, providing tissue ROI ground truth.