Table 1.
Sex (male/female) | 45/39 |
Median age (range), years | 69 (41–88) |
Newly diagnosed | 61 (73%) |
Relapsed/refractory | 23 (27%) |
Immunoglobulin class | |
IgG | 49 (58%) |
IgA | 15 (18%) |
IgD | 3 (4%) |
Light chain only | 16 (19%) |
Non-secretory | 1 (1%) |
PS (ECOG) | |
0 | 29 (35%) |
1 | 26 (31%) |
2 | 11 (13%) |
3 | 11 (13%) |
4 | 7 (8%) |
Durie and Salmon stage | |
I | 0 (0%) |
II | 26 (31%) |
III | 58 (69%) |
A | 67 (80%) |
B | 17 (20%) |
ISS stage | |
1 | 26 (31%) |
2 | 31 (37%) |
3 | 27 (32%) |
Bone scale | |
1 | 14 (17%) |
2 | 47 (56%) |
3 | 23 (27%) |
AL amyloidosis | 4 (5%) |
Anti-myeloma treatment | |
Proteasome inhibitors | 84 (100%) |
IMiDs | 59 (70%) |
ASCT | 26 (31%) |
PS performance status, ECOG Eastern Cooperative Oncology Group, ISS International Staging System, SRE skeletal-related event, IMiD immunomodulatory drug, ASCT autologous stem cell transplantation