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. 2023 Mar 1;41(3):388–403. doi: 10.1007/s00774-023-01403-4

Table 2.

Physical function and triggering factors for SRE occurrence

No. Age/Sex Amyloidosis Details of SRE Treatment response Triggers Complications/comorbidities PS ECOG
1 76/M None Femoral fracture SD

Loss of balance

Falling down

Peripheral neuropathy 2
2 47/M None

Rib fracture

Spinal cord compression

PD None None 2
3 56/M None Pelvic fracture PD

Loss of balance

Falling down

DM type 2

Orthostatic hypotension

4
4 55/M None

Vertebral fracture

Spinal cord compression

PD None Peripheral neuropathy 4
5 78/M None

Sacral fracture

Spinal cord compression

PD None None 3
6 77/M None

Vertebral fracture

Rib fracture

PD None

DM type 2

Orthostatic hypotension

1
7 74/F None Vertebral fracture PD Loss of balance Peripheral neuropathy 3
8 80/F None Vertebral fracture PD None

DM type 2

Muscle weakness

3
9 73/F None Femoral fracture SD

Loss of balance

Falling down

None 1
10 85/F None

Vertebral fracture

Spinal cord compression

PD Falling down None 1
11 59/F None Vertebral fracture PD None None 1
12 73/F Heart, tongue, skin Femoral fracture VGPR Falling down

Muscle weakness

Orthostatic hypotension

2
13 78/F GI tract, skin, muscle Vertebral fracture VGPR

Loss of balance

Falling down

Muscle weakness 1
14 70/M Heart, kidney, GI tract Rib fracture VGPR Falling down

DM type 2

Peripheral neuropathy

Orthostatic hypotension

0

M male, F female, PS performance status, ECOG Eastern Cooperative Oncology Group, VGPR very good partial response, SD stable disease, PD progressive disease, GI gastrointestinal, DM diabetes mellitus