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. 2023 Jan 17;42(5):e110468. doi: 10.15252/embj.2021110468

Figure EV3. Evaluation of Caspase‐3, ‐7 and ‐9 processing in BMDMs in response to apoptotic and pyroptotic stimuli.

Figure EV3

  • A–D
    BMDMs of the indicated genotypes were seeded at a density of 4 × 105 cells per well and primed with LPS (100 ng/ml) for 3 h before treatment with Cp. A (1 μM) or TAK1i (250 nM) for 6 h, ABT‐737 (1 μM) and CHX (20 μg/ml) for 4 h, or nigericin (10 μM) for 45–60 min. Cell lysates were harvested and analysed by western blot. Data represent 3 (A and C) or 2 (B and D) independent experiments.

Source data are available online for this figure.

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