Table 2.
Association between VLOSLP and incident dementia
| Variable | Model 1a | Model 2b | 6-month washoutb N excluded: 8756 (5%) | 1-year washoutb N excluded: 11 451 (7%) | 2-year washoutb N excluded: 15 356 (9%) |
|---|---|---|---|---|---|
| N included (%) | 169 499 (100) | 169 499 (100) | 160 743 (95) | 158 048 (93) | 154 143 (91) |
| Cox proportional hazards regression HRs for dementia by VLOSLP status (95% CI) | |||||
| VLOSLP (ref: no VLOSLP) | 4.21 (4.04–4.39) | 4.22 (4.05–4.41) | 3.12 (2.97–3.27) | 2.76 (2.62–2.91) | 2.22 (2.10–2.36) |
| Fine and Gray regression subdistribution HRs for dementia by VLOSLP status (95% CI) | |||||
| VLOSLP (ref: no VLOSLP) | 2.90 (2.80–3.03) | 2.89 (2.77–3.03) | 2.07 (1.97–2.18) | 1.82 (1.73–1.92) | 1.45 (1.37–1.53) |
| Weibull AFT model time ratios for dementia by VLOSLP status (95% CI) | |||||
| VLOSLP (ref: no VLOSLP) | 0.25 (0.24–0.27) | 0.25 (0.24–0.26) | 0.41 (0.40–0.43) | 0.46 (0.44–0.48) | 0.56 (0.54–0.58) |
a
Model 1: Adjusted for matching variable.
b
Model 2: Adjusted for VLOSLP group, sex, education level, family liability for non-affective psychotic disorder, disposable income at age 60, region of birth, and matching variable.