Fig. 3.
LPS treatment transiently decreases mitochondrial membrane potential and ATP levels, but does not result in hepatocyte death. (A) Mitochondrial membrane potential, as measured by JC-1 fluorescence red:green ratio, significantly decreased after LPS treatment, but normalized by 24 hours (*P < 0.05, compared to control). (B) Hepatocyte ATP levels decreased after LPS treatment and returned to baseline over time (*P < 0.05). (C) Hepatocyte cell number and viability were not influenced by LPS treatment over 24 hours.