Fig. 3.

Pathway and network analyses of dysregulated proteins. Network and dysregulated pathways of A Gallbladder cancer tissue compared to normal gallbladders. B Gallbladder cancer tissues compared to gallstone tissues. C Gallbladder cancer plasma compared to benign biliary pathologies plasma samples. The colour change is determined by the average Log₂ fold change of the protein. D Network analysis shows the intricate relationships between the CDPs. Red and blue indicate downregulated and upregulated proteins in GBC across the groups, respectively