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BCKDK inhibition curves of compounds tested at 15 and 200 μM ATP concentrations.Curves are representative of all replicates averaged together. Error bars indicate ± standard deviation at each concentration. (Some may not be visible when they are small). Inhibition curves of BT2 (BT2 site binder) and radicicol (ATP site binder) are used as positive controls. BCKDK, branched-chain ketoacid dehydrogenase kinase; BT2, 3,6-dichlorobenzo[b]thiophene-2-carboxylic acid.
