Table 2.
Cox proportional hazards output for GrimAgeAccel and bAgeAccel in the test datasets. Hazard ratios are presented per standard deviation of the GrimAgeAccel and bAgeAccel variables. Further details in Additional File 4: Table S11. Asterisk symbol (*) indicates the following: the FHS cohort used here was the same as the test set from the original GrimAge paper
| Cohort | N | N deaths | GrimAgeAccel Hazard ratio (95% CI) | bAgeAccel Hazard ratio (95% CI) |
|---|---|---|---|---|
| LBC193620,21 | 895 | 367 | 1.74 (1.57, 1.94) | 1.73 (1.56, 1.91) |
| LBC192120,21 | 421 | 421 | 1.33 (1.20, 1.47) | 1.44 (1.29, 1.59) |
| FHS*27,28 | 711 | 100 | 1.72 (1.35, 2.19) | 1.77 (1.40, 2.25) |
| WHI B23 White30,31 | 998 | 418 | 1.44 (1.31, 1.58) | 1.45 (1.32, 1.60) |
| WHI B23 Black30,31 | 676 | 229 | 1.35 (1.19, 1.53) | 1.42 (1.24, 1.62) |
| WHI B23 Hispanic30,31 | 433 | 118 | 1.41 (1.18, 1.68) | 1.44 (1.21, 1.72) |