Table 2.

Overlapping significant CpGs in exposure and outcome EWAS of blood lipid among survivors of European ancestry in SJLIFE cohort

CpG	chr_hg38	Start_hg38	Nearby gene gengebnegene	EWAS	Lipid	Effect	SE	P
cg00574958	11	68840153	CPT1A	Exposure	TC	− 2.25E−03	3.30E−04	2.15E−11
					TG	− 1.28E−03	1.20E−04	1.50E−24
cg05325763	11	68840250	CPT1A		TC	− 1.84E−03	3.20E−04	1.31E−08
					TG	− 1.13E−03	1.17E−04	1.48E−20
cg17058475	11	68840268	CPT1A		TC	− 2.05E−03	3.52E−04	8.81E−09
					TG	− 1.11E−03	1.31E−04	1.27E−16
ch.1.829344F	1	24657005	SRRM1	Outcome	HDL	6.39	0.89	1.03E−12
					LDL	17	2.19	2.18E−14
					TC	25.51	2.94	1.36E−17
cg20935223	7	6168606	CYTH3		HDL	8.30	1.50	3.96E−08
					LDL	22.27	3.75	3.99E−09
					TC	30.22	5.02	2.40E−09
cg21750129	9	71249778	TRPM3		HDL	7.03	1.05	3.97E−11
					LDL	15.86	2.64	2.63E−09
					TC	24.53	3.52	5.73E−12

EWAS epigenome-wide association study, chr_hg38 chromosome in GRCh38/hg38, Start_hg38 CpG start position in GRCh38/hg38, SE standard error, HDL high-density lipoprotein, LDL low-density lipoprotein, TG triglycerides, TC total cholesterol