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. 2023 Feb 28;21:70. doi: 10.1186/s12951-023-01828-z

Fig. 4.

Fig. 4

BEC-EVs and BMSC-EVs treatments enhanced ZO-1 and Claudin-5 expressions in BMV from ischemic cortex. A Representative immunofluorescent staining of Claudin-5, ZO-1 and CD31 in BMV. Scale Bar: 50 μm. Magnification: 40 × . All images were taken in the same scale. B Representative western blotting of Claudin-5 and ZO-1 in BMV and quantification of ZO-1 and Claudin-5 expressions (n = 3). ***P < 0.001 vs. SHAM group; ###P < 0.001, ##P < 0.01, #P < 0.05 vs. pMCAo group; ††P < 0.01 vs. pMCAo + BMSC-EVs group