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. 2023 Mar 1;23:413. doi: 10.1186/s12889-023-15302-w

Table 1.

Summary of the included studies

Study Participant Intervention Study
Location Age Eligibility
criteria
Sample size (completed) Platform and techniques Offered functions Methodology Mental health Measurement Mental health outcomes
Agyapong et al. [28] Canada N.A. N.A. 766 SMS text messaging Providing daily supportive messages based on CBT

Web-based survey;

Pre- and post-measurement;

6 weeks

Stress (PSS-10), Anxiety (GAD-7), Depression (PHQ-9)

Statistically significant reductions in:

- Stress (t = 3.99, p < .001)

- Anxiety (t = 9.86, p < .001)

Boucher et al. [14] United States 18–64 years Adults experiencing loneliness 11 Gamified mental health intervention Providing gamified versions of evidence-based therapeutic activities

Asynchronous focus group;

3 days

Loneliness (Open-ended discussion and

questions)

More active coping strategies (qualitatively) to address loneliness
Brog et al. [26] Germany > 18 years Adults with at least mild depressive symptoms 107 Internet-based CBT intervention Providing psychoeducational training

RCT study with waiting control group;

Pre- and post-measurement;

3 weeks

Depression (PHQ-9), Psychological distress (DASS-12), emotion regulation (SEK-27), Loneliness (UCLA Loneliness Scale), Resilience (RISC)

Statistically significant increase in:

- Emotion regulation skills (d = 0.35)

- Resilience (d = 0.38)

Bureau et al. [22] France 19–55 years Healthcare workers 10 Internet-based CBT intervention Providing psychoeducational training

Web-based survey and phone interview;

1 week

Perceived stress (phone interview) Reductions (qualitatively) in perceived stress
Charbonnier et al. [21] France N.A. University students 114 Online self-help program (via Facebook) Providing psychoeducational training

Non-randomized controlled study with control group;

Pre- and post-measurement;

8 weeks

Anxiety and depressive symptoms (HADS), Learned helplessness (LHQ)

Statistically significant reductions in:

- Anxiety (rrb = 0.49)

- Learned helplessness (rrb = 0.51)

Deng et al. [19] China 18–22 years University students 1607 Web-based physical education Providing web-based sports education during quarantine Web-based survey Depression, Anxiety, and Stress (DASS-21)

Statistically significant reductions in (compared to a previous study):

- Depression

- Anxiety

- Stress

Ellis et al. [13] Global > 18 years Adults playing certain AR games 2004 Location-based augmented reality (AR) games Promoting increased physical activity and social connection A mixed methods web-based survey Mental well-being (WHO-5, and qualitative questions)

- General improvement on mental health (77.20% participant reported);

- Improved emotional coping (42.60% participants reported)

Firdhous [25] Sri Lanka > 18 years Adults using online social media regularly 231 Online social media network Maintaining the social contacts with friends and relatives Web-based survey Social resilience (Single item question) Reduction in boredom (79.22% participants reported)
Gabrielli et al. [27] Italy 18 to 34 years University students 71 Chatbot supporting healthy coping Providing psychoeducational training

Web-based survey;

Pre- and post-measurement;

4 weeks with two per week

Perceived Stress

(PSS-10), Anxiety (GAD-7), Mindfulness (FFMQ)

Statistically significant reductions in:

- Anxiety (t = 0.94, p = .009);

- Stress (t = 2.00, p = .05)

Goodman-Casanova et al. [18] Spain > 60 years

Community-dwelling

older adults with mild cognitive impairment or mild dementia

93 Television-based assistive integrated service Providing remote support through data transmission and video interactivity between users and caregivers RCT study with control group of receiving treatment as usual General mental health (Quantitative and open-ended questions) No significant improvements in mental health
Li et al. [29] China > 18 years None 1530 Internet hospital consultation (via WeChat) Providing free internet medical consultations

Web-based survey;

Pre- and post-measurement

Psychological stress (GHQ-28), Concerns about COVID-19 (Author-generated quantitative questions)

Statistically significant reductions in

- Psychological stress (number of participants: χ2  = 1704.80, p < .001);

- Degree of concern (t = 90.64, p < .001)

Loveys et al. [16] New Zealand > 18 years Adults with an underlying medical condition or aged > 70 years with MMSE score > 24 24 Digital human facilitator (conversational agent with artificial intelligence) on website Providing cognitive behavioral and positive psychology exercises

RCT study mixed design with waitlist control group;

Pre- and post-measurement;

15 min per day over 1 week

Loneliness (UCLA Loneliness Scale); Psychological stress (PSS-4), Worry about contracting COVID-19 (Single item question); Psychological well-being (8-item Flourishing Scale) No significant improvements in mental health
Kawakami et al. [24] Japan 20–59 years Adult employees 902 COVID-19 Contact Tracing App Notifying when coming into close contact with a person with positive COVID-19 test

Web-based survey;

Pre- and post-measurement

Worry about COVID-19 (single-item scale),

Psychological distress (K6 scale)

Statistically significant reduction in psychological distress (associated with downloading app: OR = 0.61, 95%CI = [0.39–0.93], p = .02)
Pizzoli et al. [31] Italy > 18 years Adults without any impairment of auditory abilities 240 Web-based relaxation practices Offering web-based natural sounds, deep respiration, and body scans

RCT with three experimental conditions: a guided square breathing exercise, a guided body scan exercise, or natural sounds;

Pre- and post-measurement;

7 min

Perceived relaxation (VAS), Emotional states (SAM)

Statistically significant improvements (of all three interventions):

- Perceived relaxation (p < .001)

- Psychomotor activation/stress (p < .001)

- Fear related to COVID-19 (p < .001)

Ruiz-del-Solar et al. [23] Chile 15–83 years Isolated COVID-19 patients

Two hospitals;

986 visits

Telepresence robot Assisting health-care workers in providing mental and psychological health services

Qualitative field study;

8 weeks

Mental and emotional health problems (Nonparticipatory and participatory

observation, field notes, structured interviews

and anecdotal records)

Increase of positive emotions (qualitatively) in patients and health-care workers
Sharrock et al. [30] Australia > 18 years N.A. 1295 Internet-based CBT intervention Providing psychoeducational training through the story of a fictional character

Web-based survey;

Pre- and post-measurement

Health anxiety (SHAI), Depression (PHQ-9), Psychological distress (K-10)

Statistically significant reduction in:

- Health anxiety (g = 0.89)

- Psychological distress (g = 0.91)

- Depression symptoms (g = 0.55)

Shapira et al. [17] Israel > 65 years Community-dwelling older adults with internet access 82 Digital group intervention via Zoom Providing online guided sessions in small groups

A pilot-RCT study with a wait-list control group;

Pre- and post-measurement;

7 weeks with twice-weekly

Loneliness (UCLA Loneliness Scale), Depression (PHQ-9)

Statistically significant reduction in:

- Loneliness (F(1,78) = 5.59, p = .02)

- Depressive symptoms (F(1,78) = 0.57, p = .45)

Song et al. [20] China > 18 years

Adults with depression symptoms (PHQ-9 score: 5–27);

Access to smartphone

129 Mobile application based on WeChat Providing self-help storytelling to help users overcome mental health problems related to COVID-19

RCT with a wait-list control group;

Pre- and post-measurement;

1 week with three sessions

Depression (PHQ-9), Anxiety

(GAD-7), Insomnia

(ISI), Psychological resilience

(RISC), Anxiety of COVID-19 (VAS)

Statistically significant reduction in:

- Depression (F = 4.30, p = .040)

- Insomnia (F = 7.10, p = .009)

Stuart et al. [32] Australia Average age = 23.03 years N.A. 473 Socially motivated Internet use (online social connection) Providing online social connection Self-reported survey Depression (DASS) Statistically significant reduction in depression (three-way interaction between health anxiety, isolation behaviors, and Internet use for social connection: β = -0.12, p = .009)
Summers et al. [15] United Kingdom 22–70 years N.A. 347 Digital behavior change app Providing educational and therapeutic behavioral change support

Open-label survey;

Pre- and post-measurement;

12 weeks

Anxiety (GAD-7), Depression (PHQ-9), Perceived stress (PSS)

Statistically significant reduction in:

- Depression (t(272) = 15.60, p < .001)

- Anxiety (t(272) = 15.90, p < .001)

- Perceived Stress (t(272) = 22.40, p < .001)

Note: DASS-21, Depression, Anxiety, and Stress Scale; FFMQ, Five-Facet Mindfulness Questionnaire; GAD-7, Generalized Anxiety Disorder–7 scale; HADS, Hospital Anxiety and Depression Scale; IAS, Illness Attitude Scale; ISI, 7-item Insomnia Severity Index; K6, Kessler 6 scale; LHQ, Learned Helplessness Questionnaire; MMSE, Mini-Mental State Examination; PHQ-9, Patient Health Questionnaire–9; PSS-10, 10-Item Perceived Stress Scale; RCT, Randomized Controlled Trial; rrb, rank biserial correlation; SAM, Self-Assessment Manikin; SEK-27, Self-report Measure to measure emotion regulation skills; SHAI, Short Health Anxiety Inventory; RISC, Connor Davidson Resilience Scale; VAS, Visual Analogue Scales; WHO-5, World Health Organization–5 Well-Being Index