Table 1:
Patient characteristics
| Variables | Total (n = 162) | Lobectomy (n = 81) | Segmentectomy (n = 81) | P-Value |
|---|---|---|---|---|
| Sex (female), n (%) | 79 (48.7) | 39 (48.1) | 40 (49.3) | 0.875 |
| Age (years), median (IQR)] | 69 (63–74) | 68 (60–73) | 71 (65–76) | 0.037 |
| BMI (kg/m2), mean ± SD | 25.3 ± 4.3 | 25.2 ± 4.3 | 25.9 ± 4.3 | 0.814 |
| Comorbidities, n (%) | ||||
| Cardiopathy | 46 (28.4) | 20 (24.7) | 26 (32) | 0.297 |
| High blood pressure | 86 (53) | 43 (53) | 43 (53) | 1 |
| Atrial fibrillation | 18 (11) | 9 (11) | 9 (11) | 1 |
| Tobacco | 132 (81.4) | 63 (77.7) | 69 (85) | 0.228 |
| Diabetes | 23 (14.1) | 9 (11) | 14 (17.2) | 0.264 |
| Kidney failure | 16 (9.8) | 7 (8.6) | 9 (11) | 0.599 |
| Previous cancer | 65 (40.1) | 26 (32) | 39 (48.1) | 0.038 |
| Preoperative pulmonary function, mean ± SD | ||||
| FEV1 (%) | 86.03 ± 21.6 | 88.9 ± 21.1 | 86.1 ± 21.6 | 0.085 |
| DLCO (%) | 73.4 ± 22.4 | 75.8 ± 22.6 | 71.1 ± 22.3 | 0.194 |
| ASA score | 2.52 ± 0.54 | 2.53 ± 0.54 | 2.52 ± 0.54 | 0.329 |
| Histology, n (%) | ||||
| Adenocarcinoma | 125 (77.1) | 60 (74) | 65 (80) | 0.351a |
| Squamous cell carcinoma | 35 (21.6) | 19 (23.4) | 16 (19.8) | |
| Large cell tumour | 2 (1) | 2 (2) | 0 | |
| Size (mm), mean ± SD | 24.3 ± 3.1 | 25.1 ± 3.1 | 23.6 ± 3.1 | 0.001 |
| 21–25, n (%) | 114 (70.3) | 46 (56.7) | 68 (83.9) | <0.001a |
| 25–30, n (%) | 48 (29.7) | 35 (43.3) | 13 (16) | |
| Localization, n (%) | ||||
| Right upper lobe | 57 (35.2) | 33 (40.7) | 24 (29.6) | 0.186a |
| Right lower lobe | 27 (16.7) | 16 (19.8) | 11 (13.6) | |
| Left upper lobe | 52 (32.1) | 21 (25.9) | 31 (38.3) | |
| Left lower lobe | 26 (16) | 11 (13.6) | 15 (18.5) | |
| Dissected lymph nodes (n), median (IQR) | 12 (7–19) | 14 (9–23) | 10 (6–15) | <0.001 |
| Operative time (min), median (IQR) | 130 (103–157) | 131 (105–162) | 127 (100–155) | 0.432 |
| Adjuvant chemotherapy, n (%) | 15 (9.2) | 10 (12) | 5 (6.1) | 0.183 |
a
Fisher’s exact test.
ASA: American Society of Anaesthesiologists; BMI: body mass index; DLCO: diffusing capacity of the lung for carbon monoxide; FEV1: forced expiratory volume in 1 s; IQR: interquartile range; SD: standard deviation.