Table 3.
Antideterminants identified in tRNAs that prevent erroneous recognition of aaRS
| Antideterminant | tRNA (organism) | Against aaRS |
|---|---|---|
| A1–U72a | tRNATrp(E. coli) | MetRS |
| C2–G71 | tRNALeu (E. coli) | SerRS |
| G2·U71 | tRNALysb (B. burgdorferi)c | LysRS-1 |
| G3·U70 | tRNAAla (S. cerevisiae) | ThrRS |
| cyto-tRNAAla (D. melanogaster) | mt-AlaRS | |
| U30·G40 | tRNAIle (S. cerevisiae) | LysRS |
| k2C34 | tRNAIle (E. coli) | MetRS |
| C + C34 | tRNAIle (Archaea) | MetRS |
| A36 | tRNAArg (E. coli) | TrpRS |
| t6A37 | tRNAAsn (S. cerevisiae) | AspRS |
| G37 | tRNASer (S. cerevisiae) | LeuRS |
| m1G37 | tRNAAsp (S. cerevisiae) | ArgRS |
| A73 | tRNALeu (H. sapiens) | SerRS |
| G73 | tRNASer (E. coli) | LeuRS and TyrRS |
| tRNASer (H. volcanii) | LeuRS |
aA1–U72 is a context-dependent negative identity elemente; bexcept in Nanoarchaeota, found in all archaeal phyla; cprobably applies to Spirochetes (a bacterial phylum).