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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Reprod Biomed Online. 2022 May 17;45(3):519–530. doi: 10.1016/j.rbmo.2022.05.007

FIGURE 6.

FIGURE 6

Potential target genes of prolactin (PRL) signalling pathways contributing to the dysfunction of both eutopic endometrium and myometrium in women with adenomyosis. (A) Venn diagram of the differentially expressed genes (DEG) enriched to PRL signalling pathways in eutopic endometrium and myometrium. Five common target genes were identified, which consist of SHC4, CCND1, GALT, SOCS5 and ELF5; (B) the expression of CCND1 mRNA in the eutopic endometrium (P = 0.044) and myometrium (P = 0.002) of women with and without adenomyosis (n = 10 for each group); (C) the expression of GALT mRNA in the eutopic endometrium (P = 0.014) and myometrium (P = 0.282) of women with and without adenomyosis (n = 10 for each group). *P < 0.05, **P < 0.01.