Table III.

Characteristics of studies on live birth rate after ovarian tissue cryopreservation for fertility preservation included in a systematic review and meta-analysis.

Author, year of publication, country	Study design and type	Study period	Females before treatment for FP (n)	Age, years (mean/median/min–max)	Age at retrieval, years		Age at transplantation, years
					(mean ± SD)	(min–max)	(mean ± SD)	(min–max)
Oktay, 2010, USA	Prospective cohort	May 1999–March 2008	59	26.7/–/4–44	29.5	29–30	33.5	31–36
Imbert, 2014, Belgium	Retrospective cohort	March 1999–June 2011	225	24.6/–/0–37	25.3 ± 7.6		30.4 ± 6.3
Meirow, 2016, Israel	Retrospective cohort	January 2004–March 2015	20	28.7/–/14–39	28.7 ± 7.5	14–39	34.0	21–45
Silber, 2018, USA*	Retrospective cohort	1997–2017	66	–/–/–	23.7 ± 4.6		31.9 ± 3.98
Diaz-Garcia, 2018, Spain	Prospective cohort	January 2005–December 2015	800	28.2/–/–	34.3 ± 3.8		38.9 ± 4.1
Lambertini, 2018, Belgium	Retrospective cohort	January 2006–December 2016	72	–/–/–	31.5	30–33	35.5
Liebenthron, 2019, Germany	Retrospective cohort	2000–2017	30	31.1/–/–	31.1 ± 5.0		34.8 ± 4.3
Poirot, 2019, France	Retrospective cohort	2005–2015	31	26.2/27.1/16–37	26.21	16–37	33.47	24–42
Pretalli, 2019, France	Retrospective cohort	2013–2021	22	–/–/–			32.61	22–43
Dueholm Hjorth, 2020, Denmark	Retrospective cohort	2008–2013 (up to 2017)	28	29.8/–/15–39	29.8 ± 5.2	15–39	34 ± 5.1	24–42
Marklund, 2020, Sweden	Retrospective cohort	January 1995–June 2017	468	32.5/–/21–42
Dolmans, 2021, Multinational**	Retrospective cohort	up to October 2020	285	29.3/–/9–44	29.3 ± 6.2	9–44	34.6 ± 5.5
Karavani, 2021, Israel	Retrospective cohort	1997–2017	7	23.7/–/13–40	23.7
Rozen, 2021, Australia	Retrospective cohort	2006–2019	30	29.4/31/18–39	29.4	18–39	34.9
Vatel, 2021, France	Retrospective cohort	2005–2017	11	26.3/27.1/18–35	26.3 ± 6.0	18–35	33.53	24–42

^*Not included in the meta-analysis for live birth rate, FP, fertility preservation.

^**Belgium, Switzerland, Denmark, Germany, Austria, France, Spain.