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Differential gene expression between layer 3 PNs projecting to DLPFC or PPC. A) Volcano plots of genes expressed in layer 3 PNs projecting to DLPFC or PPC. B) Heat map of genes enriched in either DLPFC- or PPC-projecting layer 3 PNs. C) Principal component analysis of DEGs detected based on region of origin and projection target. Note that layer 3 PNs clearly segregate based on both on the target of their axon projection (PC1) and the type of projection (PC2).
