Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jan 31;147(5):425–441. doi: 10.1161/CIRCULATIONAHA.122.059706

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 The Authors.

Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

PMC Copyright notice

Figure 2. — Manifestations of congenital heart disease in Down syndrome. A, ECG of an individual with Down syndrome, atrioventricular septal defect (AVSD), and Eisenmenger syndrome. There is right bundle branch block, peaked P waves (P pulmonale), and extreme QRS axis. B, A complete AVSD is shown with low velocity bidirectional shunting at atrial and ventricular levels. C, Computed tomography scan of the thorax (coronal section) in a person with Eisenmenger ventricular septal defect, displaying gross cardiomegaly along with severe bronchopulmonary dysplasia. D, Axial computed tomography image from an individual with Down syndrome, obesity, and Eisenmenger syndrome with complete AVSD and a permanent pacemaker. E, Parasternal short-axis view of a trileaflet left atrioventricular valve after AVSD repair. The arrow shows the gap between the 2 bridging leaflets, which is commonly the site of regurgitation. F, Chest radiography shows a dual chamber permanent pacemaker in an individual with Down syndrome and Eisenmenger AVSD. There is severe dilation of the pulmonary vasculature, most visible on the right (arrow), and severe cardiomegaly. LA indicates left atrium; LV, left ventricle; RA, right atrium; and RV, right ventricle.