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. 2023 Mar 2;41(15):2562–2571. doi: 10.1016/j.vaccine.2023.02.059

Table 2.

Mediation Model Estimates Including Direct, Indirect, and Total Effects.

Model Path Estimate 95 % Bootstrapped Confidence Intervals
1. Race and ethnicity Direct effects on aVCI
Reference category: all non-Black, non-Asian, non-Hispanic participants (White and Other or Mixed Race) Black Race ==> aVCI −0.6* −0.8, −0.3
Hispanic Ethnicity ==> aVCI −0.3* −0.6, −0.1
Asian Race ==> aVCI −0.03 −0.5, 0.4
Covariate ==> Health Literacy
Black Race ==> Health literacy −7.6* −9.5, −5.4
Hispanic Ethnicity ==> Health literacy −7.4* −10.0, −5.0
Asian Race ==> Health literacy 3.1* 0.2, 5.0
VCI regressed on Health Literacy
Health literacy ==> aVCI 0.03* 0.01, 0.04
Indirect effects on aVCI
Black Race ==> Health literacy ==> aVCI −0.2* −0.3, −0.1
Hispanic ==> Health literacy ==>aVCI −0.2* −0.4, −0.1
Asian Race ==> Health literacy ==> aVCI 0.08* 0.02, 0.2
Total effects on aVCI
Black Race - Total effect on aVCI −0.8* −1.0, −0.5
Hispanic Ethnicity - Total effect on aVCI −0.5* −0.8, −0.3
Asian Race - Total effect on aVCI 0.05 −0.4, 0.5
2. Education Level Direct effects on aVCI
Reference: College education or greater 12th grade or less ==> aVCI −0.5 * −0.8, −0.2
Some college ==> aVCI −0.6 * −0.9, −0.2
Covariate ==> Mediator (Health Literacy)
12th grade or less ==> Health literacy −10.9* −12.8, −8.9
Some college ==> Health literacy −6.3 * −8.7, −3.9
aVCI regressed on Mediator (Health Literacy)
Health literacy ==>aVCI 0.03* 0.01, 0.04
Indirect effects on aVCI
12th grade or less ==> Health literacy ==> aVCI −0.3* −0.5, −0.1
Some college ==> Health literacy ==>aVCI −0.2* −0.3, −0.1
Total effects on aVCI
12th grade or less - Total effect on aVCI −0.7* −0.9, −0.5
Some college-Total effect on aVCI −0.7* −1.1, −0.4
3. Gender Direct effects on aVCI
Female = 1; Male = 0 Female gender ==> aVCI −0.01 −0.2, 0.2
Covariate ==> Health Literacy
Female gender ==> Health literacy 0.3 −1.7, 2.3
aVCI regressed on Health Literacy
Health literacy ==> aVCI 0.04* 0.03, 0.05
Indirect effects on aVCI
Female gender ==> Health literacy ==> aVCI 0.01 −0.07, 0.09
Total effects on aVCI
Female gender-Total effect on aVCI 0 −0.2, 0.2
4. Age continuous in years Direct effects on aVCI
Age ==> aVCI 0 −0.0, 0.01
Covariate ==> Health Literacy
Age ==> Health literacy −0.2* −0.3, −0.1
aVCI regressed on Health Literacy
Health literacy ==> aVCI 0.04* 0.03, 0.06
Indirect effects on aVCI
Age ==> Health literacy ==> aVCI −0.01* −0.01, −0.01
Total effects on aVCI
Age-Total effect on aVCI −0.01 −0.01, 0.00

Note. aVCI = Adapted Vaccine Confidence Index; Estimates are unstandardized and starred (*) if the 95 % confidence interval does not contain zero; Health Literacy is the mediator.