Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 8;56(3):e13372. doi: 10.1111/cpr.13372

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Authors. Cell Proliferation published by Beijing Institute for Stem Cell and Regenerative Medicine and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Increased maturation rates and mtDNA copy numbers in oocytes of aged mice after endometrial mesenchymal stem cell (EnMSC) mitochondrial transfer. GV oocytes from aged mice were injected with EnMSC mitochondria in human tubal fluid (HTF) in the experimental group (mito‐group) and with HTF in the control group (ctrl‐group). (A) Typical images of MII oocytes in the two groups after microinjection. Bar = 200 μm. (B) The group microinjected with mitochondria had higher maturation rates of MII oocytes than the control group. (C) The mtDNA copy numbers of oocytes in the mito‐group increased significantly after EnMSC mitochondrial supplementation compared to the numbers in the control group. In (B) and (C), the data are the mean ± SEM; n shows the number of oocytes, and asterisks (****) indicate statistically significant differences (p < 0.0001).