Table 1.
Baseline patient characteristics, by arm and age.
| Variable | Experimental condition EXG (n = 57) | Control condition CNG (n = 33) | ||||||
|---|---|---|---|---|---|---|---|---|
| MA (n = 25) | YO (n = 21) | OO (n = 11) | p value | MA (n = 6) | YO (n = 12) | OO (n = 15) | p value | |
| Age in years (M, SD) | 47.6 (10.2) | 65.5 (3.3) | 76.2 (3.7) | < 0.001* | 51.9 (5.1) | 65.2 (3.1) | 75.6 (4.5) | < 0.001* |
| Body weight in kg (M, SD) | 77.9 (13.0) | 81.8 (20.3) | 68.7 (15.5) | 0.111 | 63.3 (8.1) | 75.5 (12.4) | 68.0 (17.2) | 0.202 |
| Body mass index in kg/m2 (M, SD) | 26.6 (5.2) | 28.1 (6.7) | 25.2 (4.7) | 0.384 | 22.8 (3.3) | 26.2 (4.2) | 24.2 (5.5) | 0.326 |
| Dialysis adequacy in Kt/V (M, SD) | 1.5 (0.3) | 1.6 (0.4) | 1.6 (0.4) | 0.859 | 2.0 (0.3) | 1.9 (0.4) | 2.1 (0.3) | 0.499 |
| Over-hydration index in % (M, SD) | 11.8 (9.6) | 12.2 (5.6) | 12.0 (3.5) | 0.983 | 9.9 (7.2) | 14.3 (5.0) | 11.3 (7.8) | 0.360 |
| C-reactive protein in mg/l (M, SD) | 10.3 (14.7) | 12.6 (13.8) | 11.7 (5.2) | 0.837 | 2.9 (3.5) | 8.4 (9.2) | 12.3 (14.3) | 0.236 |
| iPTH in pg/ml (M, SD) | 495.4 (436.9.0) | 362.9 (281.3) | 196.2 (113.7) | 0.057 | 186.2 (114.3) | 467.5 (560.4) | 370.7 (338.9) | 0.407 |
| Haemoglobin in g/l (M, SD) | 112.0 (14.2) | 112.0 (11.3) | 112.2 (14.7) | 0.999 | 114.8 (5.9) | 111.8 (17.0) | 113.2 (13.9) | 0.913 |
| Albumin in g/l (M, SD) | 39.4 (2.6) | 39.1 (3.2) | 39.6 (2.0) | 0.882 | 37.3 (1.0) | 35.8 (5.7) | 37.6 (4.4) | 0.567 |
| Ferritin in ng/ml (M, SD) | 558.8 (451.7) | 609.3 (466.7) | 649.6 (749.3) | 0.881 | 878.5 (355.1) | 841.4 (358.1) | 834.9 (352.8) | 0.967 |
| Phosphates in mml/l (M, SD) | 1.8 (0.5) | 1.6 (0.3) | 1.9 (0.5) | 0.078 | 1.4 (0.3) | 1.5 (0.6) | 1.4 (0.4) | 0.710 |
| Calcium in mmol/l (M, SD) | 2.2 (0.2) | 2.2 (0.2) | 2.0 (0.3) | 0.128 | 2.3 (0.1) | 2.2 (0.1) | 2.4 (0.1) | 0.367 |
| Potassium in mEq/l (M, SD) | 5.1 (0.7) | 5.0 (0.6) | 5.5 (1.0) | 0.167 | 5.5 (0.6) | 5.1 (0.8) | 5.1 (1.0) | 0.583 |
| Sodium in mEq/l (M, SD) | 138.2 (3.8) | 138.0 (2.4) | 138.0 (2.9) | 0.949 | 138.7 (2.7) | 137.8 (2.2) | 138.6 (2.9) | 0.664 |
| Hip extension in N (M, SD) | 178.6 (55.0) | 171.3 (66.3) | 113.7 (53.4) | 0.011# | 160.3 (57.0) | 147.8 (52.6) | 133.8 (36.5) | 0.476 |
iPTH intact parathyroid hormone, N Newton, EXG experimental group, CNG control group, MA middle-aged, YO younger-old, OO older-old group. Data are presented as mean (M) ± standard deviation (SD), p values determined by analysis of variance tests. #Differences between groups significant at p < 0.05. *Differences between groups significant at p < 0.001.