TABLE 2.
Clinical features of patients with PFAPA syndrome recruited from the AIDA International Registry in the 12-month period prior to SSK12 initiation and at the last follow-up assessment.
| Clinical features | 12 months before treatment with SSK12 | Last follow-up visit | p-value |
| Headache | 17 | 9 | 0.039 |
| Pharyngitis/tonsillitis | 80 | 50 | <0.001 |
| Oral aphthae | 46 | 21 | <0.001 |
| Genital aphthae | 0 | 0 | Not performed |
| Skin manifestations | 2 | 1 | 1.000 |
| Cervical lymphadenopathy | 68 | 38 | <0.001 |
| Hepatosplenomegaly | 0 | 0 | Not performed |
| Abdominal pain | 23 | 8 | <0.001 |
| Vomiting | 5 | 0 | 0.063 |
| Diarrhea | 4 | 1 | 0.250 |
| Arthralgia/myalgia | 32 | 15 | <0.001 |
| Arthritis | 0 | 0 | Not performed |
| Serositis | 0 | 0 | Not performed |