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. 2023 Feb 16;10:1031796. doi: 10.3389/fnut.2023.1031796

TABLE 3.

Characteristics of different treatment patterns.

References Study timing Treatment patterns Number of filters Filter usage per capita Filter lifespan Study subjects Exclusion criteria
Yu et al. (26) from January 2014 to August 2015 CRRT 275 275/145 47.50 (37.75-58.58) LF CRRT for less than 24 h;
any cases with missing data
Slowinski et al. (13) from January 2008 to February 2010 CRRT 181 181/133 NR LF Former use of RCA within 72 h before the study start;
participation in other trials
Lahmer et al. (12) NR RRT 43 43/24 NR Decompensated liver cirrhosis or acute liver failure pH > 7.55 or pH < 7.1;
serum ionized calcium < 0.9 mmol/L
De Vico et al. (27) NR CRRT NR NR 49.76 ± 22.10 LF NR
Schultheiß et al. (11) From October 2009 and October 2011 CRRT 43 43/28 NR Acute LF pH > 7.55 or < 7.1;
Caion < 0.9 mmol/l
Pourcine et al. (28) From January 2014 to June 2015 RRT 67 67/41 NR Acute or chronic liver dysfunction Patients with end stage Renal disease
Rhee et al. (29) From January 1 to December 31, 2017 CRRT 104 104/32 26.0 (14.0-51.0) Liver disease CRRT for less than 24 h;
CRRT with missing data
Yu et al. (30) From January 2013 to October 2016 CRRT 79 79/41 NR LF Age < 18 years;
patients underwent LMWH anticoagulation;
patients underwent heparin anticoagulation;
patients with severe hyperlacticaemia
Klingele et al. (41) From January 2009 to November 2012 CRRT 1339 1339/69 62.2 ± 11.2 Severe liver dysfunction ICG-PDR not performed
Sponholz et al. (31) From January 2007 to December 2011 RRT 127 127/89 29 (11.0-68.0) Severe liver dysfunction NR
Saner et al. (32) From November 2004 to August 2007 CRRT NR NR 22.7 ± 14.6 LF Age < 18 years;
incomplete patient records
Durão et al. (33) From February 2004 to July 2006 RRT 418 418/143 72 ± 22.2 LF NR
Ma et al. (34) From March 2017 to June 2017 PE 203 203/54 NR HBV-ACLF Drug-induced liver injury, immune-related liver disease, alcoholic liver disease, and hyperthyroidism, and patients who were pregnant were also excluded
Berber et al. (35) From 2010 to 2021 PE 243 243/59 NR Acute toxic hepatitis hospitalized Incomplete patient records
Maheshwari et al. (36) From January 2012 to September 2015 PE NR NR NR Patients underwent therapeutic plasma exchange Patients who developed sepsis or multiorgan dysfunction prior to the PE and patients with the category IV indication, were excluded from the study
Meijers et al. (37) From August 2008 and June 2009 MARS 27 27/10 NR Acute-on-chronic liver failure Sever hypocalcemia (Ca2+ < 0.9 mmol/L);
acidosis (pH < 7.25) due to any cause
Falkensteiner et al. (38) From 2012 to 2017 MARS 75 75/49 8 (6.8-8.0) LF Age < 18 years
Faybik et al. (39) From January 2007 to May 2009 MARS 77 77/20 20 (18-22) LF Age < 18 years
Yonekawa et al. (40) NR CRRT + PE 39 39/9 NR LF NR

LF, liver failure; RRT, renal replacement therapy; CRRT, continuous renal replacement therapy; MARS, molecular adsorbent recirculation system; PE, plasma exchange; NR, not reported; RCA, regional citrate anticoagulation; Caion, ionized calcium; LMWH, low molecular weight heparin; ICG-PDR, indocyanine green plasma disappearance rate; ACLF, acute-on-chronic liver failure; HBV-ACLF, hepatitis B virus (HBV) related ACLF.