Table 1.
Baseline data: AS-TREATED
| Parameter | All (n = 344) | PVI group n = 269 |
PVI + group n = 75 |
P-value |
|---|---|---|---|---|
| Demographics | ||||
| Male sex | 251 (73%) | 195 (72%) | 56 (75%) | 0.770 |
| Age (years) | 60 ± 10 (61) | 60 ± 10 (61) | 61 ± 9 (62) | 0.421 |
| BMI (kg/m2) | 28 ± 4 (27) | 28 ± 4 (27) | 26 ± 4 (27) | 0.006 |
| Paroxysmal AF | 228 (66%) | 180 (67%) | 48 (64%) | 0.679 |
| Duration of AF (month) | 55 ± 60 (40) | 51 ± 62 (40) | 60 ± 57 (43) | 0.079 |
| PLAX (mm) | 41 ± 6 (41) | 41 ± 7 (41) | 41 ± 5 (41) | 0.618 |
| LVEF (%) | 58 ± 8 (60) | 59 ± 9 (60) | 58 ± 7 (60) | 0.917 |
| LAVI (ml/m2) | 36 ± 12 (34) | 35 ± 12 (33) | 37 ± 11 (37) | 0.073 |
| Comorbidities | ||||
| CAD | 14 (4%) | 11 (4%) | 3 (4%) | 0.755 |
| Smoking | 0.414 | |||
| Yes | 41 (12%) | 30 (11%) | 11 (15%) | |
| No | 179 (52%) | 137 (51%) | 42 (56%) | |
| Past | 120 (35%) | 98 (36%) | 22 (29%) | |
| HT | 210 (61%) | 168 (62%) | 42 (56%) | 0.349 |
| Diabetes | 25 (7%) | 21 (8%) | 4 (5%) | 0.572 |
| Renal insufficiency | 21 (6%) | 18 (7%) | 3 (4%) | 0.515 |
| CHADSVASC | 0.276 | |||
| 0 | 79 (23%) | 62 (23%) | 17 (23%) | |
| 1 | 103 (30%) | 81 (30%) | 22 (29%) | |
| 2 | 78 (23%) | 56 (21%) | 22 (29%) | |
| 3 | 50 (15%) | 42 (16%) | 8 (11%) | |
| 4 | 21 (6%) | 19 (7%) | 2 (3%) | |
| ≥ 5 | 13 (4%)I | 9 (3%) | 4 (5%) | |
| Procedural parameters | ||||
| RF-PVI at index | 244 (76%) | 187 (78%) | 73 (73%) | 0.491 |
| Procedure duration (min) | 108±40 (104) | 110 ± 42 (105) | 98 ± 34 (97) | 0.310 |
| Reconnected veins | 2.4 ± 1.1 (2) | 2.6 ± 1.0 (3) | 1.5 ± 1.0 (2) | < 0.001 |
| 0 | 15 (4%) | 2 (1%) | 13 (17%) | |
| 1 | 56 (16%) | 32 (12%) | 24 (32%) | |
| 2 | 124 (36%) | 94 (35%) | 30 (40%) | |
| 3 | 89 (26%) | 83 (31%) | 6 (9%) | |
| 4 | 60 (17%) | 58 (22%) | 2 (2%) | |
| Location | ||||
| LSPV (341) | 187 (55%) | 164 (62%) | 23 (30%) | < 0.001 |
| LIPV | 170 (49%) | 153 (58%) | 17 (22%) | < 0.001 |
| RSPV | 207 (60%) | 173 (65%) | 34 (44%) | 0.002 |
| RIPV | 237 (69%) | 198 (75%) | 39 (51%) | < 0.001 |
| RF duration | ||||
| Overall | 849±482 (769) | 859 ± 491(778) | 779 ± 416 (720) | 0.244 |
| PVI | 791± 494 (695) | 859 ± 491 (778) | 511 ± 344 (468) | < 0.001 |
| SVC | 57±142 (0) | 0 | 265 ± 196 (211) | < 0.001 |
Values are n (%) for categorical and mean ± standard deviation (median) for continuous variables
AF, atrial fibrillation; AFB, AF burden score; BMI, body mass index; CHADSVASC, (n = 343); PLAX, parasternal long-axis (n = 284); LAVI, left atrial volume indexed (n = 249); LVEF, left ventricular ejection fraction (n = 333)
Duration of AF (n = 337) was defined as the time interval between the first diagnosis of AF and pulmonary vein isolation