Table 2.

Relative OAR doses between Halcyon FFF and True Beam FFF and True Beam FF arm. Statistical significance difference at p ≤ 0.05 using paired sample t-test.

	HALFFF (%)	TBFFF (%)	TBFF (%)	p (HALFF Vs.TBFFF)	p (HALFF Vs.TBFF)	p (TBFFF Vs. TBFF)	(HAL-TB) FFF (%)	(HAL-TB) FF (%)	TB (FFF-FF) (%)
D0.2 cc
Brainstem	105.0 ± 1.5	105.7 ± 1.9	104.8 ± 1.9	0.33	0.543	0.698	− 0.5 ± 1.8	− 0.3 ± 2.4	0.2 ± 2.5
B/L Cochlea	98.5 ± 7.8	100.6 ± 3.2	100.6 ± 2.9	0.101	0.171	0.51	− 2.1 ± 7.2	− 0.9 ± 4.1	− 0.3 ± 2.9
B/L Lens	23.9 ± 10.9	25.1 ± 13.3	22.7 ± 10.4	0.412	0.315	0.786	− 1.2 ± 9.8	2.1 ± 9.2	7.1 ± 11.4
B/L Opt N	99.1 ± 6.5	97.6 ± 8.8	99.2 ± 6.3	0.076	0.506	0.461	1.4 ± 4.6	− 1.1 ± 7.6	− 0.9 ± 5.9
Opt Chiasma	102.5 ± 2.1	103.5 ± 2.8	101.7 ± 1.9	0.018	0.326	0.13	− 0.8 ± 1.8	0.4 ± 3	0.9 ± 2.7
Mean dose in %
B/L Eyes	29.2 ± 11.8	31.3 ± 14.0	31.7 ± 11.9	0.015	0.018	0.437	− 2.2 ± 5.9	− 2.2 ± 6.5	− 0.6 ± 7.3
Bladder	4.3 ± 3.8	4.7 ± 3.7	5.2 ± 3.7	0.049	0.091	0.635	− 0.4 ± 1.0	− 0.9 ± 2.6	− 0.3 ± 2.6
Duodenum	29.3 ± 14.9	29.2 ± 14.4	30.2 ± 16.4	0.938	0.856	0.955	0.2 ± 1.5	0.1 ± 6.2	− 0.1 ± 6
Oesophagus	46 ± 14.0	47.6 ± 16.7	48.4 ± 15.8	0.222	0.156	0.226	− 1.6 ± 6.1	− 4.3 ± 6.5	− 2.8 ± 4.2
B/L Femur Head	2.1 ± 2.2	2.6 ± 2.9	3 ± 2.8	0.114	0.083	0.269	− 0.3 ± 1.1	− 0.8 ± 1.2	− 0.4 ± 1.3
Bowel	20.5 ± 5.9	22.5 ± 6.2	25.3 ± 7.4	< 0.001	0.011	0.078	− 2.0 ± 1.9	− 4.7 ± 5	− 2.1 ± 4.3
Heart	16.3 ± 4.9	17.5 ± 5.6	16.5 ± 7.5	0.041	0.954	0.43	− 1.2 ± 2.7	0.3 ± 6.4	1.5 ± 7.5
B/L Kidney	16.5 ± 6.1	17.9 ± 7.5	19.3 ± 6.9	0.031	< 0.001	0.022	− 1.4 ± 3.4	− 2.8 ± 4.5	− 1.4 ± 3.9
Larynx	29.2 ± 5.0	28.2 ± 5.2	28.6 ± 5.9	0.324	0.257	0.768	1.0 ± 5.0	1.4 ± 6.4	0.5 ± 4
Liver	16.4 ± 4.4	17.4 ± 4.7	16.6 ± 4.8	< 0.001	0.035	0.459	− 1.1 ± 1.3	− 0.1 ± 4.5	1.1 ± 4.6
B/L LUNG	20.7 ± 6.9	23 ± 6.9	23.2 ± 6.3	< 0.001	< 0.001	0.544	− 2.3 ± 2.6	− 2.5 ± 3.1	− 0.2 ± 2.2
Mandible	23.2 ± 5.8	23.2 ± 6.1	24.5 ± 9.4	0.983	0.693	0.335	0.0 ± 2.1	− 1.1 ± 3.2	− 1.1 ± 2.1
Pancreas	21.7 ± 7.2	23.4 ± 6.6	24.6 ± 6.7	0.062	0.005	0.018	− 1.6 ± 2.9	− 2.8 ± 3.4	− 1.2 ± 1.9
B/L Parotid	24.8 ± 10.9	25.5 ± 11.8	25.9 ± 11.6	0.493	0.283	0.673	− 0.7 ± 6.6	− 1.1 ± 6.1	− 0.4 ± 5
Rectum	8.8 ± 5.5	10.0 ± 6.3	9.6 ± 7.2	0.02	0.327	0.906	− 1.2 ± 2.3	− 1.2 ± 5.6	0.2 ± 5.7
Stomach	17.0 ± 5.9	18.0 ± 5.5	20.1 ± 7.5	0.114	0.089	0.199	− 1.0 ± 3.2	− 3.5 ± 9.5	− 2.3 ± 8.6
Thyroid	36.6 ± 13.9	36.6 ± 16.3	36.7 ± 15	0.985	0.481	0.676	0.0 ± 4.2	1.2 ± 6.6	1.2 ± 6.6
Total Lung V5Gy (%)	43.6 ± 19.4	53.8 ± 17.4	53.6 ± 20.8	0.023	0.03	0.948	− 10.2 ± 12.6	− 9.9 ± 8.4	0.2 ± 10.8