Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 3;128(5):833–843. doi: 10.1038/s41416-022-02090-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s), under exclusive licence to Springer Nature Limited 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

PMC Copyright notice

Fig. 2 — a Knockdown effect of ST2 in HN6, Cal27 and Hsc3 by WB analysis. b Luciferase activity in CD274 promoter region after ST2 knockdown. c Transcriptome sequencing of ST2 knockdown cell lines. d ELISA showed an increased IL-33 level in medium from CAFs compared with NFs. e Overexpression of ST2 promoted IL-33-induced PD-L1 expression. f The expression and localization of PD-L1 and ST2 were analyzed by immunofluorescence staining. g The mRNA expression correlation between IL-33/ST2 and PD-L1 was analyzed by database (http://www.cbioportal.org/) and in 45 cases of oral squamous cell carcinoma. h The expression of ST2 and PD-L1 in 9 oral cancer cell lines detected by qPCR. i Expression of ST2 in PD-L1^high and PD-L1^Low sorting cell line detected by qPCR. Results are shown as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001. p = two-tailed t test.