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. 2023 Mar 1;14:1151. doi: 10.1038/s41467-023-36797-2

Fig. 4. Molecular Interactions in the optimized PTH1R-arr2 model based on the M2R-arr2 template.

Fig. 4

Two views of the model containing long-acting PTH (PTHLA, magenta), arr2 (green), and PTH1R (cyan) are presented at the center. Interactions involving the (a) distal phosphorylation cluster, (b) ICL3 of PTH1R, (c) finger loop, (d) C-loop of arr2, and (e) proximal phosphorylation cluster of PTH1R are shown in separate panels.