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. 2023 Mar 1;14(3):175. doi: 10.1038/s41419-023-05615-4

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A Schematic diagram of the experimental design for scRNA-seq. B Uniform manifold approximation and projection (UMAP) plot depicted 19,829 cells representing NPC clusters (left panel). Violin plots showed marker gene expressions across macrophage, bone marrow derived macrophage (BMDM), and Kupffer cell (KC) clusters (right panel). C Violin plots showed the expression of Zbp1 in each cell clusters. D Gene Ontology (GO) analysis was performed based on the differential expressed genes between ZBP1⁺ and ZBP1⁻ BMDMs in scRNA-seq.