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. 2023 Feb 16;13:1132757. doi: 10.3389/fcimb.2023.1132757

Figure 1.

Figure 1

RVFV genome organization. RVFV RNA genome consisting of L, M, and S RNA segments. Genomic segments are negative sense and serve as templates for the generation of complementary antigenomic RNAs. The sizes of RVFV RNA segments are: L (6404 nt), M (3885 nt), S (1690 nt). The genomic strands of L and M segments are used to transcribe the L and M mRNAs, respectively. L mRNA encodes L protein and the M mRNA encodes the Gn/Gc glycoproteins, NSm, and 78kDa protein. The S segment utilizes an ambi-sense coding strategy wherein the N mRNA is transcribed from the genomic RNA and NSs mRNA is transcribed from the antigenomic RNA. N mRNA encodes for N protein and NSs mRNA encodes for the nonstructural protein, NSs. IGR, intergenic region.