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Synaptic release in a monoaminergic neuron. Following synthesis, dopamine, serotonin, octopamine, and tyramine are packaged into synaptic vesicles by VMAT for exocytosis. Excess monoamines are recycled whole via dopamine transporter (DAT) or serotonin transporter (SERT). Extracellular monoamines can also bind to postsynaptic receptors to relay the signal downstream.
