Table 1.

Summary information of the datasets employed in the current MR study.

Traits	N	nSNP	Data type	Population	References
Gut microbiota (discovery)	18,340	NA	Continuous	72.3%European	Kurilshikov et al. (2021)
Gut microbiota (replication)	5,959	7,980,478	Continuous	European	Qin (2022)
	7,783	5,584,686	Continuous	European	Lopera-Maya et al. (2022)
Serum lipids	1,320,016	47 M	Continuous	European	Graham et al. (2022)

N, the total sample size; nSNP, number of the SNP used as the IVs for the MR analyses.