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. 2023 Feb 16;14:1122048. doi: 10.3389/fimmu.2023.1122048

Table 1.

Guidelines for HBV-infected pregnant women during pregnancy and postpartum.

Guideline Year of publication Pregnant women who should receive antiviral intervention Start antiviral intervention gestational week First-choice antiviral drug Puerpera when should discontinue the antiviral intervention Postpartum monitoring
European Association for the Study of the Liver (EASL) (7) 2017 HBV DNA >200,000 IU/ml or HBsAg >10,000 IU/ml 24–28 weeks TDF Continue for up to 12 weeks after delivery
American Association for the Study of Liver Diseases (AASLD) (4) 2018 HBV DNA >200,000 IU/ml 28–32 weeks TDF Immediately after delivery to 3 months postpartum Postpartum 6 months for hepatitis flares and seroconversion
Chinese Society of Infectious Diseases, Chinese Medical Association (6) 2019 HBV DNA >200,000 IU/ml 24–28 weeks TDF Immediately after delivery or continue up to 1–3 months postpartum Up to postpartum 6 months
Asian Pacific Association for the Study of Liver (APASL) (5) 2022 HBV DNA >200,000 IU/ml 24–28 weeks TDF Immediately after delivery or continue up to 12 weeks postpartum At least 24 weeks for hepatitis fare and rebound of HBV DNA