Fig. 3.

Differential gene expression analysis between LoY and RoY. (A) Volcano plot for kidney chromophobe with Y-linked genes highlighted. Genes that show a p-value smaller than 0.05 and an absolute log2 fold change> 2 are colored in red. (B) Heatmap shows genes that are either significantly up- or downregulated in LoY of kidney chromophobe compared to RoY (p-value smaller than 0.05 and log2FC above or below 2). Samples are arranged in columns, genes in rows. Top indicates Y chromosome status of each tumor, left indicates Y chromosomal or autosomal location of a gene and up or down regulation in LoY.