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. 2023 Feb 16;10:1011045. doi: 10.3389/fmed.2023.1011045

TABLE 2.

Multiple linear regression analyses of the associations between serum cotinine (≥10 ng/mL) and lipid-related indices.

Independent variable cotinine levels (≥10 ng/mL)a n = 32
Dependent variables β SE P R 2 f 2
CHOLb 0.001 0.002 0.40 0.12
HDL-cb [log] −0.001 0 0.04* 0.39 0.65**
LDL-cb 0.002 0.001 0.29 0.17
TGb [log] 0 0.001 0.48 0.27
CRI-Ib [log] 0.001 0 0.03* 0.38 0.62**
ACb [log] 0.001 0.001 0.03* 0.39 0.64**

*P is considered significant at <0.05. Bolded values mean statistically significant results.

aLevel for cotinine (≥10 ng/mL) were considered reliable indicators for cigarette smoke.

bDependent variables in separate multiple linear regression equations with covariates including age, diabetes medications, gender, statins, and waist circumference.

AC, atherogenic coefficient; β, regression coefficient; CHOL, total cholesterol; CRI-I, Castelli risk index-I; f2, Cohen’s effect size; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol; R2, coefficient of determination; SE, standard error, TG, Triglycerides.

**f2 = R2/1-R2 calculated for significant regression models.