TABLE 1.
LncRNAs involved in TIME of GC disease.
| LncRNA | Expression | Pathway | References |
|---|---|---|---|
| LINC00001 | Upregulated in GC tissuses | miR-497/MACC1 axis | Ma et al. (2017) |
| LINC00008 | Upregulated in GC tissuses | miR-138/E2F2 axis | Yu et al. (2020) |
| LINC00023 | Downregulated in GC tissuses | p53 signaling pathway | Wei and Wang (2017) |
| LINC00047 | Upregulated in GC tissuses | PI3K/AKT pathway | Zhu et al. (2019) |
| LINC00152 | Upregulated in GC tissuses | EGFR-dependent pathway | Zhou et al. (2015) |
| LINC00256A | Upregulated in GC tissuses | FAM225A-miR-206-ADAM12 axis | Chen et al. (2021) |
| LINC00342 | Upregulated in GC tissuses | miR-545-5p/CNPY2 axis | Liu and Yang (2021) |
| LINC00902 | Downregulated in GC tissuses | p53 and mIR-23b | Qi et al. (2015) |
| LINC01082 | Upregulated in GC tissuses | suppressed GC cells and PD-L1 | Wang et al. (2022f) |
| LINC01540 | Upregulated in GC tissuses | miR-378 to modulate MAPK1 expression | Diao et al. (2018) |
| LINC-POU3F3 | Upregulated in GC tissuses | TGF-beta signal pathway | Xiong et al. (2015) |
| HIF1A-AS2 | Upregulated in GC tissuses | HIF1A-AS2/RP11-366L20.2-miR-29c axis | Nai et al. (2022) |
MACC1: metastasis-associated in colon cancer 1; E2F2: E2F transcription factor 2; PI3K: phosphatidylinositol 3-kinase; EGFR: epidermal growth factor receptor; ADAM12: A disintegrin and metalloprotease 12; CNPY2: canopy FGF signaling regulator 2; MAPK1: mitogen-activated protein kinase 1; TGF-beta: transforming growth factor-beta.