Effects of 326E on lipid levels in blood of HFHC diet induced hyperlipidemia. (A) Schematic diagram of 326E for hyperlipidemia treatment. Briefly, male golden hamsters were induced by HFHC diet for 2 weeks. Animals then received 326E or BA treatment for another 2 weeks (n = 8). HFHC diet, high fat high cholesterol diet (normal chow supplemented with 0.5% cholesterol, 23% fat and 5% fructose, w/w); (B) Body weight gain were shown after 326E treatment for 2 weeks; (C)–(F) Serum levels of TG (C), TC (D), LDL-C (E), and HDL-C (F) before and during the treatment period were shown. The oral dose of BA was 30 mg/kg. Data are mean ± SEM; ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 compared to Veh.